Reductive Heck reactions of N-arylamino-substituted tricyclic imides
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Abstract
The C–C coupling of (3aR,4S,7R,7aS)-rel-2-[(3-chloro-4-fluorophenyl)amino]-3a,4,7,7a-tetrahydro-4,7-methano-1H-isoindole-1,3(2H)-dione (3) which was prepared as a new starting material and (3aR,4S,7R,7aS)-rel-2-[(2,4--dinitrophenyl)amino]-3a,4,7,7a-tetrahydro-4,7-methano-1H-isoindole-1,3(2H)-dione (6) with aryl- and heteroaryl iodides gave the aryl(hetaryl), N-arylamino tricyclic imides 4a–d and 7a–d under reductive Heck conditions.
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