Synthesis and crystal structure of copper(II) complexes with pyridoxal S-methylisothiosemicarbazone bearing a new coordination mode

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Marko V. Rodić
Mirjana M. Radanović
Ljiljana S. Vojinović-Ješić
Svetlana K. Belošević
Željko K. Jaćimović
Vukadin M. Leovac


The reaction of copper(II) nitrate and pyridoxal S-methylisothio­semi­carbazone (PLITSC) in the presence of ammonium thiocyanate resulted in the formation of two types of complexes. A dimeric complex of the formula [{Cu(m-PLITSC)NCS}2](NCS)2·2MeOH was obtained in the presence of excess of ammonium thiocyanate, while in the presence of its nearly equimolar amount, crystals of a polymeric complex {[Cu(m-PLITSC)NCS]NO3∙MeOH}n were formed. The complexes were characterized by elemental analysis, con­ductometry, IR spectroscopy, and their structures are unequivocally determined by single crystal X-ray crystallography. In both complexes, the copper atom is five-coordinated, situated in a deformed square-pyramidal environment. The basal plane of the square pyramid is defined by the oxygen atom of the depro­tonated phenol group and terminal nitrogen atoms of the isothiosemicarbazide moiety of the Schiff base, as well as the nitrogen atom of the coordinated thio­cyanate ion, while the apical site is occupied by the oxygen atom of the hydro­xy­methyl group of the neighboring asymmetric unit. This coordination mode of the PLITSC was hitherto unknown. A survey of the Cambridge Structural Database showed that the coordination of the hydroxy­methyl group is rare within pyridoxal-based Schiff base metal complexes.


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M. V. Rodić, M. M. Radanović, L. S. Vojinović-Ješić, S. K. Belošević, Željko K. Jaćimović, and V. M. Leovac, “Synthesis and crystal structure of copper(II) complexes with pyridoxal S-methylisothiosemicarbazone bearing a new coordination mode”, J. Serb. Chem. Soc., vol. 84, no. 5, pp. 467–476, Jun. 2019.
Inorganic Chemistry
Author Biography

Marko V. Rodić, University of Novi Sad, Faculty of Sciences, Trg D. Obradovića 3, 21000 Novi Sad

Assistant Professor
Chair of Physical Chemistry

Department of Chemistry, Biochemistry and Environmental Protection
Faculty of Sciences
University of Novi Sad


S. Padhyé, G. B. Kauffman, Coord. Chem. Rev. 63 (1985) 127 (

J. S. Casas, M. S. Garcı́a-Tasende, J. Sordo, Coord. Chem. Rev. 209 (2000) 197 (

T. S. Lobana, R. Sharma, G. Bawa, S. Khanna, Coord. Chem. Rev. 253 (2009) 977 (

H. Beraldo, D. Gambino, Mini-Reviews Med. Chem. 4 (2004) 31 (

C. B. Scarim, D. H. Jornada, M. G. M. Machado, C. M. R. Ferreira, J. L. dos Santos, M. C. Chung, Eur. J. Med. Chem. 162 (2019) 378 (

B. Atasever, B. Ülküseven, T. Bal-Demirci, S. Erdem-Kuruca, Z. Solakoğlu, Invest. New Drugs 28 (2010) 421 (

D. X. West, S. B. Padhye, P. B. Sonawane, Structural and physical correlations in the biological properties of transition metal heterocyclic thiosemicarbazone and S-alkyldithiocarbazate complexes, in Complex Chemistry, Structucture and Bonding book series, Vol. 76, Springer, Berlin, 1991, pp. 1–50 (

C. Santini, M. Pellei, V. Gandin, M. Porchia, F. Tisato, C. Marzano, Chem. Rev. 114 (2014) 815 (

V. M. Leovac, V. S. Jevtović, L. S. Jovanović, G. A. Bogdanović, J. Serb. Chem. Soc. 70 (2005) 393 (

M. Revenco, P. Bulmaga, E. Jora, O. Palamarciuc, V. Kravtsov, P. Bourosh, Polyhedron 80 (2014) 250 (

V. M. Leovac, G. A. Bogdanović, V. I. Češljević, V. Divjaković, Acta Crystallogr., C: Cryst. Struct. Commun. 56 (2000) 936 (

V. M. Leovac, V. I. Češljević, J. Serb. Chem. Soc. 59 (1994) 13

G. A. Bogdanović, A. Spasojević-de Biré, B. V. Prelesnik, V. M. Leovac, Acta Crystallogr., C: Cryst. Struct. Commun. 54 (1998) 766 (

V. M. Leovac, R. Herak, B. Prelesnik, S. R. Niketic, J. Chem. Soc., Dalt. Trans. (1991) 2295 (

N. V. Gerbeleu, Y. A. Simonov, V. B. Arion, V. M. Leovac, K. I. Turta, K. M. Indrichan, D. I. Gradinaru, V. E. Zavodnik, T. I. Malinovskii, Inorg. Chem. 31 (1992) 3264 (

V. Arion, K. Wieghardt, T. Weyhermueller, E. Bill, V. Leovac, A. Rufinska, Inorg. Chem. 36 (1997) 661 (

U. Knof, T. Weyhermüller, T. Wolter, K. Wieghardt, J. Chem. Soc., Chem. Commun. (1993) 726 (

J. S. Casas, M. D. Couce, J. Sordo, Coord. Chem. Rev. 256 (2012) 3036 (

V. M. Leovac, L. S. Vojinović-Ješić, S. A. Ivković, M. V. Rodić, L. S. Jovanović, B. Holló, K. M. Szécsényi, J. Serb. Chem. Soc. 79 (2014) (

V. M. Leovac, V. S. Jevtović, G. A. Bogdanović, Acta Crystallogr., C: Cryst. Struct. Commun. 58 (2002) m514 (

Rigaku Oxford Diffraction, CrysAlisPro Software system, Rigaku Corporation, Oxford, 2018

G. M. Sheldrick, Acta Crystallogr., A: Found. Adv. 71 (2015) 3 (

G. M. Sheldrick, Acta Crystallogr., C: Struct. Chem. 71 (2015) 3 (

C. B. Hübschle, G. M. Sheldrick, B. Dittrich, J. Appl. Crystallogr. 44 (2011) 1281 (

A. L. Spek, Acta Crystallogr., D: Biol. Crystallogr. 65 (2009) 148. (

L. J. Farrugia, J. Appl. Crystallogr. 45 (2012) 849 (

W. J. Geary, Coord. Chem. Rev. 7 (1971) 81 (

K. Nakamoto, Infrared and Raman spectra of inorganic and coordination compounds. Part B, Applications in coordination, organometallic, and bioinorganic chemistry, Wiley, New York, 2009, pp. 92–127

C. R. Groom, I. J. Bruno, M. P. Lightfoot, S. C. Ward, Acta Crystallogr., B: Struct. Sci. Cryst. Eng. Mater. 72 (2016) 171 (

M. B. Ferrari, F. Bisceglie, G. Pelosi, P. Tarasconi, R. Albertini, P. P. DallAglio, S. Pinelli, A. Bergamo, G. Sava, J. Inorg. Biochem. 98 (2004) 301 (

P. Adak, B. Ghosh, A. Bauzá, A. Frontera, A. J. Blake, M. Corbella, C. Das Mukhopadhyay, S. K. Chattopadhyay, RSC Adv. 6 (2016) 86851 (

L. S. Vojinović-Ješić, M. V. Rodić, B. Barta Holló, S. A. Ivković, V. M. Leovac, K. Mészáros Szécsényi, J. Therm. Anal. Calorim. 123 (2016) 2069 (

M. M. Lalović, L. S. Vojinović-Ješić, L. S. Jovanović, V. M. Leovac, V. I. Češljević, V. Divjaković, Inorg. Chim. Acta 388 (2012) 157 (

M. Belicchi-Ferrari, F. Bisceglie, C. Casoli, S. Durot, I. Morgenstern-Badarau, G. Pelosi, E. Pilotti, S. Pinelli, P. Tarasconi, J. Med. Chem. 48 (2005) 1671 (

S. Mandal, Y. Sikdar, R. Sanyal, S. Goswami, J. Mol. Struct. 1128 (2017) 471 (

K. Aoki, H. Yamazaki, J. Chem. Soc., Chem. Commun. (1987) 1241 (

S. A. Ivković, L. S. Vojinović-Ješić, V. M. Leovac, M. V. Rodić, S. B. Novaković, G. A. Bogdanović, Struct. Chem. 26 (2015) 269 (

R. R. Holmes, Five-Coordinated Structures, in Progress in Inorganic Chemistry, Vol. 32, S. J. Lippard, Ed., Wiley, New York, 1984, pp. 119–235 (

V. Chaurin, E. C. Constable, C. E. Housecroft, New J. Chem. 30 (2006) 1740 (

D. Vidovic, A. Radulovic, V. Jevtovic, Polyhedron 30 (2011) 16 (

J. C. A. Boeyens, J. Cryst. Mol. Struct. 8 (1978) 317 (

D. Cremer, J. A. Pople, J. Am. Chem. Soc. 97 (1975) 1354 (

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