Porous amphiphilic biogel from facile chemo-biosynthetic route


  • Syed Mohammad Daniel Syed Mohamed Institute of Biological Sciences, Faculty of Science University of Malaya, Kuala Lumpur 50603
  • M. Suffian M. Annuar Institute of Biological Sciences, Faculty of Science University of Malaya, Kuala Lumpur 50603 http://orcid.org/0000-0003-3387-0160
  • Thorsten Heidelberg Department of Chemistry, Faculty of Science University of Malaya, Kuala Lumpur 50603
  • Nor Faezah Ansari Department of Biotechnology, Kulliyyah of Science, International Islamic University Malaysia, Bandar Indera Mahkota 25200 Kuantan, Pahang
  • Nor Hidayah Ismail Research Cluster Office, Institute of Research Management and Services, University of Malaya, 50603 Kuala Lumpur




biogel, chemo-biosynthetic, biopolymer, radical grafting


Grafting of medium-chain-length poly-3-hydroxyalkanoates (mcl-PHA) with glycerol 1,3-diglycerolate diacrylate (GDD) in acetone was per­formed using benzoyl peroxide as the initiator. A detailed mechanism scheme provides significant improvement to previous literature. Radical-mediated grafting generated ab carbon inter-linking of mcl-PHA and GDD, resulting in a macromolecular structure with gel properties. The thermal properties of the copolymer for different graft yields were investigated as a function of initiator concentration, GDD monomer concentration, incubation period and tempera­ture. The water absorption and porosity of the gel were significantly improved relative to neat mcl-PHA.


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How to Cite

S. M. D. Syed Mohamed, M. S. M. Annuar, T. Heidelberg, N. F. Ansari, and N. H. Ismail, “Porous amphiphilic biogel from facile chemo-biosynthetic route”, J. Serb. Chem. Soc., vol. 85, no. 3, pp. 353-367, Mar. 2020.