@article{Thach_Le_Nguyen_Dang_Dang_Nguyen_2020, place={Belgrade, Serbia}, title={Synthesis of sulfonamides bearing 1,3,5-triarylpyrazoline and 4-thiazolidinone moieties as novel antimicrobial agents}, volume={85}, url={https://www.shd-pub.org.rs/index.php/JSCS/article/view/7000}, DOI={10.2298/JSC180621057T}, abstractNote={<p class="AbstractChar">Two series of sulfonamides were synthesized from 4-hydrazinyl­ben­zenesulfonamide as the key starting material. 1,3,5-Tri­arylpyrazoline sulfon­amides (<strong>2a</strong>–<strong>i</strong>) were obtained by cyclocondensation of various chalcones in 53–64 % yields, while 4-thiazolidinone derivatives (<strong>4a</strong>–<strong>e</strong>) were synthesized by cyclocondensation between mercaptoacetic acid and different phenylhydra­zones in 43–62 % yields. The synthesized compounds were characterized based on FTIR, 1H-NMR, 13C-NMR and HRMS data. The sulfonamides were evaluated for their in vitro antimicrobial activities against four bacterial strains (E. coli, P. aeruginosa, B. subtillis and S aureus), two filamentous fungal strains (A. niger and F. oxysporum) and two yeast strains (C. albicans and S. cerevisiae). Seven pyrazolines, <strong>2a</strong>–<strong>c</strong> and <strong>2e</strong>–<strong>h</strong>, exhibited significant inhibition of different microbial strains. Among them, compound <strong>2b</strong> displayed good anti­fungal activity against A. niger (MIC value at 12.5 mg mL-1) over the reference drug.</p>}, number={2}, journal={Journal of the Serbian Chemical Society}, author={Thach, Thi-Dan and Le, T. Tuong-Vi and Nguyen, H. Thien-An and Dang, Chi-Hien and Dang, Van-Su and Nguyen, Thanh-Danh}, year={2020}, month={Mar.}, pages={155–162} }