A 7-year experience in core needle biopsy of breast lesions: Correlation between imaging and hematoxylin and eosin-stained sections Scientific paper

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Milena Šunjević
Dunja Popović
Sara Medić
Milana Panjković
Branimir Gudurić


Screening mammography is an imaging procedure which allows breast cancer detection in its early stage. The Breast Imaging and Reporting Data System (BI-RADS) determined six radiological categories for describing lesions. The core needle biopsy (CNB) is minimally invasive procedure that provides pathohistological samples. Via microscopic analysis, samples are cat­egor­ized into five groups according to the B system for pathohistological rep­ort. The aim of the study was to follow the spectrum of pathohistological diagnoses; to define which BI-RADS and core categories are most commonly expressed in certain age groups; and to determine the incidence of histological diagnoses in different BI-RADS categories. The study included 631 patients and data was analysed in order to localise the lesion, BI-RADS and core cat­egory and pathohistological diagnosis. Within 631 biopsies, 33 diagnoses were given. In each age group, the findings indicating a high risk for malignancy were the most common (>2 %). The highest percentage of malignant categories was found in patients over the age of 61. Final diagnoses showed a deviation compared to the radiological categories, especially in BI-RADS4 category. Pathohistological diagnosis is always a definite confirmation of a breast lesion type and it has significant contribution to the evaluation of CNB quality.


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M. Šunjević, D. Popović, S. Medić, M. Panjković, and B. Gudurić, “A 7-year experience in core needle biopsy of breast lesions: Correlation between imaging and hematoxylin and eosin-stained sections: Scientific paper”, J. Serb. Chem. Soc., vol. 89, no. 5, pp. 657–665, May 2024.
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