Sustainable synthesis of silver nanoparticles on cotton gauze for enhanced antibacterial properties Scientific paper

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Darka D. Marković
https://orcid.org/0000-0001-8707-195X
Vanja B. Tadić
https://orcid.org/0000-0003-1761-604X
Ana R. Žugić
https://orcid.org/0000-0002-7722-6169
Maja M. Radetić

Abstract

Wound protection is a critical step in preventing or reducing infections, as well as in preventing the transmission of infections between patients. Wound dres­sings are essential medical products that cover wounds and facilitate healing. The present study examines the possibility of using Ag nanoparticles (NPs) to impart antibacterial activity to cotton gauze, a commonly used disposable wound dressing material. The in situ synthesis of Ag-based NPs on cotton gauze was achieved using extracts from Populus x euramericana (PE) and Ailanthus altissima (Mill.) Swingle (AA) leaves. Major phytochemical compounds in the extracts were quan­tified using HPLC. FESEM and EDS mapping analyses confirmed the presence of Ag-based NPs across the fibre surfaces of both samples. The average size of NPs synthesized in the presence of PE and AA extracts was 88±26 and 82±23 nm, respectively. A comparable amount of silver was found in the sample obtained with PE (14.22±0.23 µmol/g) and in the sample synthesized using AA extract (13.63±1.40 µmol/g). The synthesized samples achieved maximum bacterial reduction against Gram-negative bacteria Escherichia coli and Gram-positive Staphylococcus aureus.

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[1]
D. D. Marković, V. B. Tadić, A. R. Žugić, and M. M. Radetić, “Sustainable synthesis of silver nanoparticles on cotton gauze for enhanced antibacterial properties: Scientific paper”, J. Serb. Chem. Soc., vol. 90, no. 12, pp. 1495–1511, Dec. 2025.
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Materials

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