Synthesis and spectral characterization of novel 1,5-benzodiazepine oxime derivatives

Main Article Content

Lina Rekovic
Lidija Kosychova
Irina Bratkovskaja
Regina Vidziunaite

Abstract

Three new 1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one oximes were synthesized and characterized by the methods of 1H- and 13C-NMR, IR and elemental analysis. Along with previously described compounds bearing one additional methyl group on the 5th nitrogen atom, the new compounds were characterized in bulk by UV–Vis and fluorescence spectroscopy in various sol­vents. The influence of the nature of the organic solvent on the spectra of the title compounds was investigated and is discussed.

Article Details

How to Cite
[1]
L. Rekovic, L. Kosychova, I. Bratkovskaja, and R. Vidziunaite, “Synthesis and spectral characterization of novel 1,5-benzodiazepine oxime derivatives”, J. Serb. Chem. Soc., vol. 84, no. 4, pp. 343-353, Apr. 2019.
Section
Organic Chemistry
Author Biographies

Lina Rekovic, Institute of Biochemistry, Life Sciences Center, Vilnius University, Saulėtekio al. 7, Vilnius 10223, Lithuania, phone: +370 5 223 4391

PhD student at Department of Bioanalysis, Institute of Biochemistry, Life Sciences Center, Vilnius University, Lithuania

Lidija Kosychova, Institute of Biochemistry, Life Sciences Center, Vilnius University, Saulėtekio al. 7, Vilnius 10223, Lithuania, phone: +370 5 223 4391

Associate professor at Klaipeda University, Faculty of Marine Engineering, Lithuania; researcher at Institute of Biochemistry, Life Sciences Center, Vilnius University, Vilnius, Lithuania

Irina Bratkovskaja, Institute of Biochemistry, Life Sciences Center, Vilnius University, Saulėtekio al. 7, Vilnius 10223, Lithuania, phone: +370 5 223 4391

Junior research fellow at Institute of Biochemistry, Life Sciences Center, Vilnius University, Vilnius, Lithuania

Regina Vidziunaite, Institute of Biochemistry, Life Sciences Center, Vilnius University, Saulėtekio al. 7, Vilnius 10223, Lithuania, phone: +370 5 223 4391

Senior research fellow at Institute of Biochemistry, Life Sciences Center, Vilnius University, Vilnius, Lithuania

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