Antibacterial properties of thalloid liverworts Marchantia polymorpha L., Conocephalum conicum (L.) Dum. and Pellia endiviifolia (Dicks.) Dumort Scientific paper

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Ivana Ivković
Danka Bukvički
Miroslav Novaković
Stefan Ivanović
Olja Stanojević
Ivan Nikolić
Milan Veljić


The antimicrobial activity of methanol extracts of three thalloid liver­worts, Marchantia polymorpha, Conocephalum conicum and Pellia endiviifolia and bis-bibenzyl marchantin A, the most dominant compound in the methanol extract of M. polymorpha, have been investigated in this research. 1H-NMR spec­troscopy revealed that the M. polymorpha and P. endiviifolia extracts of liverwort contain terpenes, oils, sugars and bis-bibenzyls, while these specific macrocyclic compounds were absent in the C. conicum extract. The anti­mic­robial potential was tested on eight bacterial strains. Antimicrobial effects of extracts and mar­chantin A were observed against Gram-positive bacteria, while they showed no effect against Gram-negative bacteria in both methods used – well diffusion and broth microdilution.


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I. Ivković, “Antibacterial properties of thalloid liverworts Marchantia polymorpha L., Conocephalum conicum (L.) Dum. and Pellia endiviifolia (Dicks.) Dumort: Scientific paper”, J. Serb. Chem. Soc., vol. 86, no. 12, pp. 1249–1258, Dec. 2021.
Theme issue honoring Professor Emeritus Slobodan Milosavljević's 80th birthday


R. M. Schuster, The Hepaticae and Anthocerotae of North America, Vol. I, Columbia University Press, New York, NY, 1966 (ISBN: 9780231028141)

X. He, Y. Sun, R. L. Zhu, Crit. Rev. Plant Sci. 32 (2013) 293 (

Y. Asakawa, A. Ludwiczuk, F. Nagashima, Phytochemistry 91 (2013) 52 (

A. Upadhyay, I. Upadhyaya, A. Kollanoor-Johny, K. Venkitanarayanan, Biomed Res. Int. 2014 (2014) 1 (

Y. Asakawa, M. Toyota, M. Tori, T. Hashimoto, J. Spectrosc. 14 (2000) 149 (

I. Dimkić, P. Ristivojević, T. Janakiev, T. Berić, J. Trifković, D. Milojković-Opsenica, S. Stanković, Ind. Crop. Prod. 94 (2016) 856 (

A. Klančnik, S. Piskernik, B. Jeršek, S. Smole Možina, J. Microbiol. Methods 81 (2010) 121 (

M. Toyota, Yakugaku Zasshi 120 (2000) 1359 (

Y. Asakawa, T. Takemoto, Phytochemistry 18 (1979) 285 (

M. Toyota, T. Saito, Y. Asakawa, Phytochemistry 43 (1996) 1087 (

N. Liu, D. X. Guo, Y. Y. Wang, L. N. Wang, M. Ji, H. X. Lou, Nat. Prod. Commun. 6 (2011) 49 (

T. Hashimoto, H. Suzuki, M. Tori, Y. Asakawa, Phytochemistry 30 (1991) 1523 (

I. Ivković, M. Novaković, M. Veljić, M. Mojsin, M. Stevanović, P. D. Marin, D. Bukvički, Plants 10 (2021) 1063 (

L. Mizzi, D. Maniscalco, S. Gaspari, C. Chatzitzika, R. Gatt, V. P. Valdramidis, Lett. Appl. Microbiol. 71 (2020) 251 (

J. Chifre, G. Scarmato, L. Herszage, Lancet 8271 (1982) 560 (

K. D. Millar, B. J. Crandal-Stotler, J. F. S. Ferreira, K. V. Wood, Cryptog. Bryol. 28 (2007) 197

E. H. Lahlou, T. Hashimoto, Y. Asakawa, J. Hattori Bot. Lab. 88 (2000) 271 (

S. D. Lorimer, N. B. Perry, R. S. Tangney, J. Nat. Prod. 56 (1993) 1444 (

Z. Q. Lu, P. H. Fan, M. Ji, H. X. Lou, J. Asian Nat. Prod. Res. 8 (2006) 187 (

D. Wang, R.-L. Zhu, L. Qu, Cryptog. Bryol. 27 (2006) 343

Y. Asakawa, in Phytochemicals in Human Health Protection, Nutrition, and Plant Defense, J. Romeo, Ed., Kluwer Academic/Plenum Publishers, New York, NY, 1999, p. 319 (

N. Mewari, P. Kumar, Pharm. Biol. 46 (2008) 819 (

M. Singh, S. Singh, V. Nath, V. Sahu, A. K. S. Rawat, Pharm. Biol. 49 (2011) 526 (

R. Castaldo-Cobianchi, S. Giordano, A. Basile, U. Violante, G. Bot. Ital. 122 (1988) 303 (

M. Vujicic, I. Dimkic, A. Sabovljević, S. Stankovic, M. Sabovljević, Acta Biol. Planta Agrien. 5 (2017) 63 (

A. Dey, S. Mukherjee, A. De, J. Herbs Spices Med. Plants 21 (2015) 102 (

V. Nikolajeva, L. Liepina, Z. Petrina, G. Krumina, M. Grube, I. Muiznieks, Adv. Microbiol. 2 (2012) 345 (

E. Kamory, G. M. Keseru, B. Papp, Planta Med. 61 (1995) 387 (

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